Associations of CXCL1 gene 5’UTR variations with ovarian cancer
نویسندگان
چکیده
منابع مشابه
Associations between Gene Expression Variations and Ovarian Cancer Risk Alleles Identified from Genome Wide Association Studies
Functional genetic variations play important roles in shaping phenotypic differences among individuals through affecting gene expression, and thus, very likely to influence disease susceptibility, such as cancer susceptibility. One critical question in this era of post-genome wide association studies (GWAS) is how to assess the functional significance of the genetic variations identified from G...
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background ovarian cancer is the most common fatal gynecologic malignancy in women. the brca2 gene has a role in regulation of cell cycle during proliferation, differentiation and dna repair. changes in the methylation of brca2 may be an effective mechanism for ovarian cancer. objectives the aim of the present study was to evaluate the association between ovarian cancer and methylation status o...
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ژورنال
عنوان ژورنال: Journal of Ovarian Research
سال: 2020
ISSN: 1757-2215
DOI: 10.1186/s13048-020-00640-9